Standard dosages

≥ 18 years

Weight	ROA	Load	Dosage
	ROA: po	Load: -	Dosage: 90/400mg 1 dd
Comments: = 1 tablet per dag

Kidney function

≥ 18 years

ROA	GFR	Dosage	Interval	Comments
ROA: po
	GFR: <30	Dosage: veiligheid en effectiviteit niet bewezen

Renal elimination: ledipasvir: 1% sofosbuvir: 80%

Dosage: dependent on kidney function

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

• http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
• http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16

For individual advice, consult an expert on site.

Metadata

Swab vid: M-343591.1
Updated: 06/16/2019 - 20:05
Status: Published

External links

• Farmacotherapeutisch Kompas - Ledipasvir_sofosbuvir

Menu position

• antiviral