imipenem + cilastatine
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DH - Carbapenems -> J01DH51 - Imipenem And Enzyme Inhibitor
Administration category:
Free
Medicine group:
antibacterial
Brand name:
Tienam
Safety margins
| Weight | ROA | Dosage | |
|---|---|---|---|
|
ROA: iv |
Dosage: min. 250mg 4 dd to max. 1000mg 4 dd |
||
|
Comments:
dosisadvies heeft betrekking op imipenem component |
|||
Dosage for "I" sensitivity
| Weight | ROA | Load | Dosage | |
|---|---|---|---|---|
|
ROA: iv |
Load: - |
Dosage: 1000mg 4 dd |
||
|
Comments:
dosisadvies heeft betrekking op imipenem component |
||||
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 10 - 30 |
Dosage: 50% |
Comments: normale oplaaddosis |
||
|
GFR: <10 |
Dosage: 50% |
Comments: normale oplaaddosis |
||
Renal elimination:
70%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: normale oplaaddosis, gevolgd door 50% van de normale dosis, 4 dd
Hemo dialysis: normale oplaaddosis, gevolgd door 50% van de normale dosis, 4 dd
CAV / VVHD: normale oplaaddosis, gevolgd door 50% van de normale dosis, 4 dd
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1495.7
Updated: 01/15/2024 - 12:21
Status: Published